PITDB is a publicly available database for sharing results from published PIT (proteomics informed by transcriptomics) experiments. The PIT approach  involves the analysis of a given sample by both RNA-seq and proteomic mass spectrometry followed by sequence-level integration of the acquired data to provide an unprecedented insight into which genomic elements are being transcribed and translated within a given sample. The benefit of this approach is that any expressed polypeptide can be detected, unlike traditional proteomics which is constrained to searching spectra against a list of known protein sequences.
We define a TGE as an amino acid chain produced from a genomic locus through the processes of transcription and translation. The typical example of a TGE is a protein, encoded by a gene. However, other types of TGE have been reported in the literature, such as short open reading frames (sORF) and products of so-call non coding RNA (ncRNA).
You can browse the experiments and samples that make up PITDB by clicking Browse in the top right of the PITDB web interface. More usefully, you to access specific information in PITDB via four simple searches:
Detailed information from a particular database view can be downloaded for further analysis by clicking the relevant Download button above the table of interest and selecting the items that you want to download, and the format you want to download them in.
We welcome submission of data to PITDB, in support of published work. To begin a submission, click Submission in the top right of PITDB web interface and follow the instructions.